Sedatives and Hypnotics · Pharmacology

Buspirone is unique among anxiolytics because it:

  1. Produces anxiolysis within minutes of the first oral dose
  2. Lacks sedative effects and does not produce physical dependence
  3. Works by increasing chloride conductance at the GABA-A receptor channel
  4. Is the drug of choice for acute panic attacks and status epilepticus
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Correct answer: Lacks sedative effects and does not produce physical dependence

Buspirone is a partial agonist at 5-HT1A receptors. Unlike benzodiazepines, it lacks sedative, anticonvulsant, and muscle-relaxant properties, making it useful for chronic generalized anxiety disorder without the risk of addiction.

Difficulty: Medium Question 9 of 20

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