Which of the following is a serious, idiosyncratic adverse effect of Felbamate, limiting its use to only the most severe, refractory cases of epilepsy?
Show answer and explanation
Correct answer: Acute liver failure and aplastic anemia
Felbamate is associated with a high incidence of aplastic anemia and acute hepatic failure. Because of these life-threatening risks, it is reserved for patients whose seizures cannot be controlled by any other means.
Keep practicing
More Antiepileptics questions
- Which antiepileptic agent is a water-soluble prodrug that can be given by intramuscular injection, avoiding the local tissue necrosis seen…
- Gabapentin and Pregabalin do not act directly on GABA receptors. Instead, they bind to which target?
- Primidone is an older antiepileptic drug that is metabolized into two active metabolites, one of which is:
- Which of the following is a potential side effect of Valproic acid that requires monitoring of the patient's amylase and lipase levels?
- Zonisamide is contraindicated in patients with a known allergy to which class of drugs?
- Which antiepileptic drug acts as a selective antagonist at the AMPA glutamate receptor?