Antiepileptics · Pharmacology

Which of the following is a potential side effect of Valproic acid that requires monitoring of the patient's amylase and lipase levels?

  1. Hepatotoxicity
  2. Acute pancreatitis
  3. Thrombocytopenia
  4. Hyperammonemic encephalopathy
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Correct answer: Acute pancreatitis

Valproic acid carries a warning for life-threatening acute pancreatitis. Patients presenting with severe abdominal pain, nausea, and vomiting while on valproate must be evaluated for this complication.

Difficulty: Medium Question 17 of 20

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