Which of the following describes the primary mechanism of action of Selective Serotonin Reuptake Inhibitors (SSRIs)?
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Correct answer: Inhibiting the SERT protein to raise synaptic serotonin
SSRIs specifically bind to and inhibit the serotonin transporter (SERT). This prevents the reuptake of serotonin into the presynaptic terminal, thereby increasing the concentration of the neurotransmitter available to bind to postsynaptic receptors.
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