Cholinergic Agonists · Pharmacology

Which of the following describes the primary mechanism of action of Bethanechol?

  1. Irreversible inhibition of acetylcholinesterase
  2. Direct activation of muscarinic receptors
  3. Direct activation of nicotinic receptors
  4. Inhibition of acetylcholine reuptake
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Correct answer: Direct activation of muscarinic receptors

Bethanechol is a direct-acting cholinergic ester that selectively stimulates muscarinic receptors. It is structurally related to acetylcholine but is resistant to hydrolysis by acetylcholinesterase, allowing for a longer duration of action.

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