Which of the following agents is a tertiary amine and can cross the blood-brain barrier, making it the preferred antidote for Atropine poisoning?
Show answer and explanation
Correct answer: Physostigmine
Unlike Neostigmine and Pyridostigmine, which are quaternary amines, Physostigmine is a tertiary amine. Its lipid solubility allows it to enter the central nervous system to reverse both central and peripheral anticholinergic toxicity.
Keep practicing
More Cholinergic Agonists questions
- What is the primary mechanism of action of organophosphate insecticides like Malathion and Parathion?
- A patient presents with excessive salivation, lacrimation, urination, and miosis after accidental pesticide exposure. Which medication shou…
- Which of the following medications is a carbamate used for the long-term management of Myasthenia Gravis because of its intermediate durati…
- The 'Methacholine Challenge Test' is used clinically to diagnose which condition?
- Which of the following is a symptom of 'cholinergic crisis' resulting from overdosage of acetylcholinesterase inhibitors?
- Donepezil and Rivastigmine are used in the treatment of Alzheimer’s disease. What is their intended pharmacological effect?