Cholinergic Agonists · Pharmacology

A patient presents with excessive salivation, lacrimation, urination, and miosis after accidental pesticide exposure. Which medication should be administered to reactivate the acetylcholinesterase enzyme?

  1. Atropine
  2. Pralidoxime
  3. Scopolamine
  4. Ipratropium
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Correct answer: Pralidoxime

Pralidoxime (2-PAM) is a cholinesterase reactivator that can pull the phosphate group off the enzyme if administered before aging occurs. It is used alongside Atropine, which manages the symptomatic muscarinic overstimulation.

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