Cholinergic Agonists · Pharmacology

Which of the following medications is a carbamate used for the long-term management of Myasthenia Gravis because of its intermediate duration and lack of CNS effects?

  1. Donepezil
  2. Pyridostigmine
  3. Tacrine
  4. Methacholine
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Correct answer: Pyridostigmine

Pyridostigmine is a quaternary ammonium compound that does not cross the blood-brain barrier. Its intermediate duration (3–6 hours) makes it suitable for managing the muscle weakness associated with Myasthenia Gravis.

Difficulty: Medium Question 8 of 20

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