Donepezil and Rivastigmine are used in the treatment of Alzheimer’s disease. What is their intended pharmacological effect?
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Correct answer: To increase the levels of acetylcholine in the brain
Alzheimer's is associated with a loss of cholinergic neurons. These drugs inhibit acetylcholinesterase in the CNS, increasing the availability of acetylcholine to improve cognitive function and memory.
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