Which tetracycline is specifically used off-label to treat the Syndrome of Inappropriate Antidiuretic Hormone (SIADH) because it inhibits the action of ADH?
Show answer and explanation
Correct answer: Demeclocycline
Demeclocycline induces a state of nephrogenic diabetes insipidus by interfering with the intracellular signaling of ADH in the renal collecting duct. This property makes it useful for managing hyponatremia in SIADH patients.
Keep practicing
More Tetracyclines questions
- Tigecycline belongs to which subclass of tetracyclines designed to overcome common resistance mechanisms?
- Which of the following substances should be avoided when taking oral tetracyclines because they decrease the drug's absorption?
- Which tetracycline is associated with dose-related vestibular toxicity, manifesting as dizziness, vertigo, and nausea?
- Tetracyclines are the first-line treatment for which of the following infections?
- A patient experiences severe epigastric pain and 'pill esophagitis' after taking Doxycycline. What advice would have prevented this?
- Which condition is a known risk when using expired or outdated tetracyclines?