Tetracyclines · Pharmacology

A patient taking Doxycycline for acne develops a severe sunburn-like rash after brief sun exposure. This is an example of which side effect?

  1. Type I hypersensitivity
  2. Urticaria
  3. Fixed drug eruption
  4. Phototoxicity
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Correct answer: Phototoxicity

Tetracyclines, especially Demeclocycline and Doxycycline, are known to cause phototoxic reactions. These drugs absorb UV light in the skin, leading to the formation of free radicals that cause skin damage.

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