Which of the following substances should be avoided when taking oral tetracyclines because they decrease the drug's absorption?
Show answer and explanation
Correct answer: Dairy products and antacids containing Mg, Al, or Ca
Tetracyclines form insoluble chelates with multivalent cations ($Ca^{2+}, Mg^{2+}, Al^{3+}, Fe^{2+}$). This chemical interaction significantly reduces the bioavailability of the antibiotic.
Keep practicing
More Tetracyclines questions
- Which tetracycline is associated with dose-related vestibular toxicity, manifesting as dizziness, vertigo, and nausea?
- Tetracyclines are the first-line treatment for which of the following infections?
- A patient experiences severe epigastric pain and 'pill esophagitis' after taking Doxycycline. What advice would have prevented this?
- Which condition is a known risk when using expired or outdated tetracyclines?
- What is the primary route of elimination for Tetracycline (the parent drug of the class)?
- Which of the following is a potential complication of high-dose intravenous tetracycline therapy, particularly in pregnant women?