Tetracyclines · Pharmacology

A patient experiences severe epigastric pain and 'pill esophagitis' after taking Doxycycline. What advice would have prevented this?

  1. Take the medication with a full glass of water and remain upright
  2. Take the medication with a large glass of milk
  3. Take the medication only at bedtime just before lying down
  4. Crush the tablet and mix it with applesauce or another soft food before swallowing
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Correct answer: Take the medication with a full glass of water and remain upright

Tetracycline capsules and tablets can cause local mucosal irritation and ulceration if they lodge in the esophagus. Staying upright and using plenty of water helps ensure the medication reaches the stomach.

Difficulty: Medium Question 11 of 20

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