What is the primary mechanism of action of tetracyclines in inhibiting bacterial growth?
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Correct answer: Reversible binding to the 30S ribosomal subunit to block aminoacyl-tRNA entry
Tetracyclines are bacteriostatic antibiotics that bind to the 30S subunit of the bacterial ribosome. This prevents the attachment of aminoacyl-tRNA to the A site, thereby halting protein synthesis.
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