A patient with a Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency is at risk for which complication when taking sulfonamides?
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Correct answer: Hemolytic anemia
Sulfonamides act as oxidizing agents. In patients with G6PD deficiency, red blood cells cannot produce enough NADPH to maintain reduced glutathione, leading to oxidative damage and hemolysis.
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