Resistance to fluoroquinolones often involves mutation in:
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Correct answer: Bacterial DNA gyrase
Fluoroquinolones target DNA gyrase and topoisomerase IV. Mutations in these enzymes reduce drug binding and lead to resistance.
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More Drug Resistance Mechanisms questions
- Extended-spectrum beta-lactamases (ESBLs) confer resistance to:
- Methicillin-resistant Staphylococcus aureus (MRSA) is resistant due to:
- Which mechanism reduces antibiotic entry into Gram-negative bacteria?
- Which resistance mechanism is most associated with aminoglycosides?
- Resistance to sulfonamides occurs due to:
- Which of the following best describes cross-resistance?