Which mechanism reduces antibiotic entry into Gram-negative bacteria?
Show answer and explanation
Correct answer: Porin channel mutation
Mutations in porin channels reduce permeability of the outer membrane in Gram-negative bacteria. This limits antibiotic entry into the cell.
Keep practicing
More Drug Resistance Mechanisms questions
- Which resistance mechanism is most associated with aminoglycosides?
- Resistance to sulfonamides occurs due to:
- Which of the following best describes cross-resistance?
- Biofilm formation contributes to antimicrobial resistance by:
- Which enzyme enables some Gram-negative bacteria to hydrolyse imipenem and meropenem?
- Resistance due to mutation in ribosomal proteins mainly affects which drug class?