Methicillin-resistant Staphylococcus aureus (MRSA) is resistant due to:
Show answer and explanation
Correct answer: Acquisition of mecA gene encoding altered PBP2a
MRSA carries the mecA gene, which encodes a modified penicillin-binding protein (PBP2a). This protein has low affinity for beta-lactam antibiotics.
Keep practicing
More Drug Resistance Mechanisms questions
- Which mechanism reduces antibiotic entry into Gram-negative bacteria?
- Which resistance mechanism is most associated with aminoglycosides?
- Resistance to sulfonamides occurs due to:
- Which of the following best describes cross-resistance?
- Biofilm formation contributes to antimicrobial resistance by:
- Which enzyme enables some Gram-negative bacteria to hydrolyse imipenem and meropenem?