Resistance to sulfonamides occurs due to:
Show answer and explanation
Correct answer: Altered dihydropteroate synthase
Sulfonamides inhibit dihydropteroate synthase in folate synthesis. Mutation or acquisition of altered forms of this enzyme reduces drug binding.
Keep practicing
More Drug Resistance Mechanisms questions
- Which of the following best describes cross-resistance?
- Biofilm formation contributes to antimicrobial resistance by:
- Which enzyme enables some Gram-negative bacteria to hydrolyse imipenem and meropenem?
- Resistance due to mutation in ribosomal proteins mainly affects which drug class?
- Which mechanism is associated with multidrug resistance (MDR)?
- Which process enables bacteria to acquire resistance genes from bacteriophages?