Antitubercular Drugs · Pharmacology

Which of the following side effects is a common, harmless occurrence associated with Rifampin that patients should be counseled about?

  1. Yellowing of the skin and sclera
  2. Orange-red discoloration of urine, sweat, and tears
  3. Temporary darkening of the skin and mucous membranes
  4. A persistent metallic taste in the mouth
Show answer and explanation

Correct answer: Orange-red discoloration of urine, sweat, and tears

Rifampin is itself an orange-red compound and is excreted in urine, sweat, saliva, and tears. The resulting discoloration is harmless, but patients should be warned in advance because it can be alarming and can permanently stain soft contact lenses.

Difficulty: Medium Question 6 of 20

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