Rifampin is a potent inducer of which enzyme system, leading to numerous drug-drug interactions?
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Correct answer: Cytochrome P450
Rifampin is one of the most powerful inducers of the hepatic cytochrome P450 system, especially CYP3A4. Induction speeds the metabolism and lowers the efficacy of many co-administered drugs, including oral contraceptives, warfarin, and protease inhibitors.
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