Antitubercular Drugs · Pharmacology

In the standard 6-month 'short-course' regimen for drug-susceptible TB, which drugs are typically used during the initial 2-month phase?

  1. Isoniazid and Rifampin alone
  2. Isoniazid, Rifampin, and Pyrazinamide
  3. Isoniazid, Rifampin, Pyrazinamide, and Ethambutol
  4. Rifampin, Pyrazinamide, Streptomycin, and Ethambutol
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Correct answer: Isoniazid, Rifampin, Pyrazinamide, and Ethambutol

The intensive phase of the standard short-course regimen uses the four RIPE drugs, rifampin, isoniazid, pyrazinamide, and ethambutol, for the first 2 months. A 4-month continuation phase with isoniazid and rifampin alone then completes the 6-month course.

Difficulty: Medium Question 12 of 20

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