What is the primary mechanism of action for Ethambutol?
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Correct answer: Inhibition of the enzyme arabinosyl transferase
Ethambutol inhibits arabinosyl transferases, the enzymes that polymerize arabinose into arabinogalactan in the mycobacterial cell wall. The resulting wall defect increases permeability and impairs bacterial growth. ATP synthase is the target of bedaquiline and RNA polymerase that of rifampin.
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