Paromomycin is an aminoglycoside that is uniquely used for the treatment of:
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Correct answer: Intestinal amebiasis and Leishmaniasis
Paromomycin is not absorbed from the gut, making it effective for treating intestinal parasitic infections like amebiasis and cryptosporidiosis. It is also used topically or parenterally for certain forms of leishmaniasis.
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More Aminoglycosides questions
- Which of the following describes the primary mechanism of action for aminoglycosides?
- Why are aminoglycosides largely ineffective against obligate anaerobic bacteria?
- Which pharmacokinetic property allows for 'once-daily dosing' of aminoglycosides despite their relatively short half-lives?
- Aminoglycosides are known for their narrow therapeutic index. Which two major toxicities are most commonly associated with this class?
- Which aminoglycoside is the most commonly used for systemic infections and serves as the prototype for the class?
- The synergistic effect observed when combining an aminoglycoside with a cell-wall synthesis inhibitor (like Penicillin) is primarily due to: