Which of the following describes the primary mechanism of action of non-selective NSAIDs?
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Correct answer: Reversible inhibition of cyclooxygenase-1 and cyclooxygenase-2
Most NSAIDs, such as ibuprofen and naproxen, work by reversibly inhibiting both COX-1 and COX-2 enzymes. This prevents the conversion of arachidonic acid into pro-inflammatory prostaglandins and thromboxanes.
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