What are 'Hirano bodies,' which are frequently observed in the hippocampus of Alzheimer patients?
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Correct answer: Intracellular eosinophilic, actin-rich paracrystalline inclusions
Hirano bodies are bright eosinophilic, rod-like inclusions found in the pyramidal cells of the hippocampus. They are primarily composed of actin and are a non-specific finding often seen in AD and normal aging.
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