Carcinogenesis · Pathology

Which oncogenic virus is strongly associated with the development of Kaposi sarcoma in immunocompromised patients?

  1. Epstein-Barr Virus (EBV)
  2. Human T-cell Lymphotropic Virus (HTLV-1)
  3. Human Herpesvirus 8 (HHV-8)
  4. Hepatitis B Virus (HBV)
Show answer and explanation

Correct answer: Human Herpesvirus 8 (HHV-8)

HHV-8, also known as Kaposi Sarcoma-associated Herpesvirus (KSHV), encodes proteins that mimic cellular growth factors and inhibit p53, leading to the proliferation of endothelial cells in HIV/AIDS patients.

Difficulty: Medium Question 8 of 20

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