Carcinogenesis · Pathology

Which of the following describes the 'Warburg Effect' in cancer cells?

  1. Shift from aerobic respiration to oxidative phosphorylation
  2. Preferential use of aerobic glycolysis for energy production
  3. Complete cessation of ATP production
  4. Reliance on protein catabolism for all metabolic needs
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Correct answer: Preferential use of aerobic glycolysis for energy production

The Warburg Effect is a metabolic hallmark where cancer cells switch to glycolysis even in the presence of ample oxygen. This provides the metabolic intermediates (carbon skeletons) necessary for the rapid synthesis of cellular components.

Difficulty: Medium Question 14 of 20

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