A skin biopsy shows large, cup-shaped, umbilicated papules containing eosinophilic cytoplasmic inclusions (Henderson-Paterson bodies). What is the diagnosis?
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Correct answer: Molluscum contagiosum
Molluscum contagiosum is caused by a poxvirus. The large, ellipsoid Henderson-Paterson bodies compress the nucleus and fill the cytoplasm of the keratinocytes in the characteristic umbilicated lesion.
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