Tissue Processing · Pathology

What is the most common clearing agent used in routine histopathology laboratories?

  1. Chloroform
  2. Benzene
  3. Xylene
  4. Cedarwood oil
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Correct answer: Xylene

Xylene is the most widely used clearing agent because it is rapid in action and efficiently removes alcohol from the tissue. However, prolonged exposure to xylene can make tissues brittle, so timing must be carefully controlled.

Difficulty: Medium Question 4 of 20

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