Fixatives · Pathology

Acetone is most commonly used as a fixative for:

  1. Large routine surgical specimens
  2. Brain tissue for Alzheimer's research
  3. Frozen sections and enzyme histochemistry
  4. Bone marrow trephine biopsies
Show answer and explanation

Correct answer: Frozen sections and enzyme histochemistry

Acetone is a rapid, dehydrating fixative that is often used at cold temperatures (4°C) to preserve enzymes and cell surface antigens in frozen sections or cytology smears.

Difficulty: Medium Question 13 of 20

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