Anemia Classification · Pathology

Which index is used to distinguish between an anemia caused by decreased red cell production and one caused by increased red cell destruction?

  1. Corrected Reticulocyte Count
  2. Mean Corpuscular Hemoglobin (MCH)
  3. Hematocrit
  4. Total Iron Binding Capacity (TIBC)
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Correct answer: Corrected Reticulocyte Count

The reticulocyte count indicates the bone marrow's response to anemia. A high corrected reticulocyte count suggests hemolysis or blood loss (regeneration), while a low count suggests a production defect like nutritional deficiency or marrow failure.

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