Macrocytic anemias are further sub-classified into megaloblastic and non-megaloblastic types based on the presence of:
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Correct answer: Hypersegmented neutrophils
Megaloblastic macrocytic anemia, typically caused by B12 or folate deficiency, is characterized by impaired DNA synthesis. This results in larger RBCs and the presence of hypersegmented neutrophils (five or more lobes).
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More Anemia Classification questions
- Which of the following is a classic cause of normocytic anemia with an elevated reticulocyte count?
- A peripheral blood smear shows 'Schistocytes' (fragmented red cells). This finding is most suggestive of which anemia classification?
- In the classification of microcytic anemias, which condition is characterized by a defect in globin chain synthesis?
- A patient with chronic rheumatoid arthritis develops anemia. Lab results show a low TIBC and high Serum Ferritin. This fits the profile of:
- Which finding on a peripheral smear would help classify an anemia as 'Hereditary Spherocytosis'?
- What is the primary classification for an anemia caused by acute, massive hemorrhage within the first few hours?