Anemia Classification · Pathology

A peripheral blood smear shows 'Schistocytes' (fragmented red cells). This finding is most suggestive of which anemia classification?

  1. Microcytic anemia due to thalassemia
  2. Macrocytic anemia due to alcohol use
  3. Microangiopathic Hemolytic Anemia (MAHA)
  4. Normocytic anemia due to chronic renal failure
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Correct answer: Microangiopathic Hemolytic Anemia (MAHA)

Schistocytes result from mechanical shearing of RBCs as they pass through fibrin thrombi in small vessels. This is a hallmark of microangiopathic hemolytic anemias, such as TTP or DIC.

Difficulty: Medium Question 6 of 20

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