Localized amyloid deposition in type 2 diabetes mellitus occurs in pancreatic islets and is composed primarily of which protein?
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Correct answer: Islet amyloid polypeptide
In type 2 diabetes mellitus, amyloid deposits in pancreatic islets are derived from islet amyloid polypeptide, also known as amylin. These deposits are associated with beta-cell dysfunction.
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More Amyloidosis questions
- Which of the following best explains organ dysfunction in systemic amyloidosis?
- Which of the following best describes the biochemical nature of amyloid deposits?
- Congo red staining of amyloid deposits under polarized light demonstrates which characteristic feature?
- AL amyloidosis is most commonly associated with which underlying condition?
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