AL amyloidosis is most commonly associated with which underlying condition?
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Correct answer: Multiple myeloma
AL amyloidosis is caused by deposition of immunoglobulin light chains, often produced by a plasma cell dyscrasia such as multiple myeloma. Excess light chains misfold and deposit in tissues.
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More Amyloidosis questions
- AA amyloidosis most frequently develops secondary to which of the following?
- In systemic amyloidosis, which organ is most commonly affected leading to nephrotic syndrome?
- Beta-amyloid deposits in the brain are characteristically associated with which condition?
- Which precursor protein is responsible for AA amyloid formation?
- Dialysis-associated amyloidosis is primarily due to accumulation of which protein?
- Which cardiac manifestation is commonly seen in patients with systemic amyloidosis?