Amyloidosis · Pathology

Congo red staining of amyloid deposits under polarized light demonstrates which characteristic feature?

  1. Metachromasia
  2. Apple-green birefringence
  3. Yellow fluorescence
  4. Blue-black nuclear staining
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Correct answer: Apple-green birefringence

Amyloid stained with Congo red shows apple-green birefringence under polarized light. This optical property results from the organized beta-pleated sheet structure of amyloid fibrils.

Difficulty: Medium Question 2 of 20

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