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Inflammatory Bowel Disease · Pathology

Which of the following is true regarding smoking and IBD?

  1. Smoking is a risk factor for both Crohn and UC
  2. Smoking is protective against Crohn disease but increases the risk of UC
  3. Smoking increases the risk of Crohn disease but may be protective against UC
  4. Smoking has no significant impact on the progression of either disease
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Correct answer: Smoking increases the risk of Crohn disease but may be protective against UC

There is a paradoxical relationship where smoking increases the risk and severity of Crohn disease, whereas it appears to lower the risk of developing Ulcerative Colitis or lessen its severity.

Difficulty: Medium Question 16 of 20

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