A 24-year-old female presents with bloody diarrhea and tenesmus. Colonoscopy reveals diffuse mucosal inflammation that is most severe in the rectum. Which histological feature is most likely to be seen?
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Correct answer: Crypt abscesses with neutrophilic infiltration
Ulcerative Colitis primarily affects the mucosa and submucosa, commonly presenting with crypt abscesses where neutrophils collect in the lumens of the colonic crypts. Rectal involvement is nearly universal in Ulcerative Colitis.
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More Inflammatory Bowel Disease questions
- Which of the following describes the distribution of inflammation in Crohn disease?
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- Which histological finding, if present, is highly suggestive of Crohn disease and essentially excludes a diagnosis of Ulcerative Colitis?
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