Inflammatory Bowel Disease · Pathology

The 'Lead Pipe' sign in Ulcerative Colitis is due to:

  1. Severe calcification of the colon wall
  2. Loss of haustral folds due to chronic inflammation and fibrosis
  3. Transmural fat deposition
  4. Acute muscular spasm in the rectum
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Correct answer: Loss of haustral folds due to chronic inflammation and fibrosis

Chronic inflammation in UC leads to shortening of the colon and loss of the normal haustral markings. On imaging, the colon appears as a smooth, featureless tube, resembling a lead pipe.

Difficulty: Medium Question 19 of 20

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