Cell Junctions · Histology

What is the primary role of the protein 'vimentin' in the context of cell junctions in non-epithelial cells?

  1. It forms the strands of tight junctions.
  2. It is a transmembrane protein in gap junctions.
  3. It is the primary sugar coating on the glycocalyx.
  4. It anchors desmosomes in mesenchymal cells.
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Correct answer: It anchors desmosomes in mesenchymal cells.

While epithelial cells use keratin, mesenchymal cells (like fibroblasts) use vimentin as their intermediate filament. Vimentin provides the structural scaffold to which desmosome-like junctions attach in these cell types.

Difficulty: Medium Question 13 of 20

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