Cell Junctions · Histology

Which junctional structure is most likely to be affected by toxins from the bacteria Vibrio cholerae?

  1. Macula occludens
  2. Macula adherens
  3. Zonula occludens
  4. Zonula adherens
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Correct answer: Zonula occludens

Cholera toxin and other enteric pathogens often target the zonula occludens (tight junctions). By disrupting these seals, the bacteria increase paracellular permeability, leading to massive fluid loss and diarrhea.

Difficulty: Medium Question 19 of 20

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