The 'plaque' seen on the cytoplasmic side of a desmosome is primarily composed of which proteins?
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Correct answer: Desmoplakin and Plakoglobin
The attachment plaque of a desmosome is a dense region of proteins including desmoplakin and plakoglobin. These proteins act as the interface that secures the cytokeratin intermediate filaments to the transmembrane desmogleins.
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