Epithelial Tissue

Cell Junctions Practice Questions

20 free Cell Junctions practice questions for the Histology, each with the correct answer and a detailed explanation. Open any question below, or take the full set as an interactive quiz.

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20 questions
  1. Q1. Which of the following cell junctions is primarily responsible for preventing the paracellular passage of water and solutes between epithelial cells?
  2. Q2. The 'terminal bar' visible under a light microscope in the apical region of intestinal epithelial cells represents which complex?
  3. Q3. Which transmembrane protein is the most critical for maintaining the structural integrity of the Zonula adherens?
  4. Q4. Which of the following junctions allows for the direct chemical and electrical communication between adjacent cells through the passage of small ions and molec…
  5. Q5. A desmosome (macula adherens) is histologically characterized by its attachment to which cytoskeletal element?
  6. Q6. Which junctional structure anchors the basal surface of an epithelial cell to the underlying basal lamina?
  7. Q7. The autoimmune disease Pemphigus vulgaris involves the production of antibodies against which junctional component?
  8. Q8. In a gap junction, six transmembrane proteins assemble to form a half-channel called a:
  9. Q9. Which of the following proteins is a major component of the tight junction (zonula occludens) and determines its selective permeability to specific ions?
  10. Q10. Focal adhesions are cell-matrix junctions that primarily link the extracellular matrix to which intracellular structure?
  11. Q11. Which junctional complex component is responsible for maintaining the 'apical-basolateral polarity' of epithelial cells?
  12. Q12. The 'fascia adherens' is a type of anchoring junction specifically found in which tissue?
  13. Q13. What is the primary role of the protein 'vimentin' in the context of cell junctions in non-epithelial cells?
  14. Q14. Calcium ions are required for the function of which group of junctional proteins?
  15. Q15. Which of the following is an intracellular adapter protein that links integrins to actin in focal adhesions?
  16. Q16. Bullous pemphigoid is a blistering disease caused by autoantibodies attacking which structure?
  17. Q17. Under electron microscopy, which junction displays a characteristic '7-layered' (septilaminar) appearance where adjacent cell membranes are separated by an ext…
  18. Q18. The 'plaque' seen on the cytoplasmic side of a desmosome is primarily composed of which proteins?
  19. Q19. Which junctional structure is most likely to be affected by toxins from the bacteria Vibrio cholerae?
  20. Q20. In the small intestine, the zonula adherens is located immediately basal to which other junction?