Cell Junctions · Histology

Under electron microscopy, which junction displays a characteristic '7-layered' (septilaminar) appearance where adjacent cell membranes are separated by an extremely narrow cleft?

  1. Desmosome
  2. Hemidesmosome
  3. Zonula adherens
  4. Gap junction
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Correct answer: Gap junction

In a gap junction, the two plasma membranes are separated by a very narrow space of only 2-3 nanometers. This close apposition creates a distinctive septilaminar (seven-layered) pattern in high-magnification TEM images.

Difficulty: Medium Question 17 of 20

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