Interstitial Growth · Histology

Why is interstitial growth possible in cartilage but generally NOT in mature bone?

  1. Cartilage matrix is flexible and expandable, but bone is rigidly calcified.
  2. Bone cells completely lack the ability to undergo mitotic cell division.
  3. Cartilage has a rich blood supply that promotes faster rates of cell division.
  4. Mature bone lacks a perichondrium or periosteum for generating new cells.
Show answer and explanation

Correct answer: Cartilage matrix is flexible and expandable, but bone is rigidly calcified.

The hydrated, proteoglycan-rich matrix of cartilage is flexible enough to allow internal expansion as cells divide. In contrast, the mineralized hydroxyapatite of bone prevents cells from moving apart after division.

Difficulty: Medium Question 4 of 20

Practice all 20 Interstitial Growth questions

Keep practicing

More Interstitial Growth questions