Interstitial Growth · Histology

In embryonic development, the initial formation of a 'cartilage model' begins with which process?

  1. Appositional growth from the perichondrial surface
  2. Endochondral ossification of the mesenchyme
  3. Mesenchymal condensation and interstitial growth
  4. Calcification and mineralization of the perichondrium
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Correct answer: Mesenchymal condensation and interstitial growth

Embryonic cartilage formation starts with the condensation of mesenchyme into chondrogenic nodules. These cells differentiate into chondrocytes and immediately begin expanding the model via interstitial growth.

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