Interstitial Growth · Histology

During interstitial growth, what physical change occurs to the isogenous groups over time?

  1. They fuse together to form a large multinucleated syncytium.
  2. They undergo apoptosis progressively, leaving behind empty lacunae.
  3. They are pushed apart as they secrete new territorial matrix.
  4. They dedifferentiate and gradually transform into active fibroblasts.
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Correct answer: They are pushed apart as they secrete new territorial matrix.

As daughter cells in an isogenous group secrete new matrix components, they create individual lacunae. This process effectively expands the cartilage mass from the inside out.

Difficulty: Medium Question 6 of 20

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