Which of the following describes the 'Zone of Calcified Cartilage'?
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Correct answer: A zone where chondrocytes die as the matrix calcifies.
As the cartilage matrix becomes calcified, nutrients can no longer reach the chondrocytes. This leads to the death (apoptosis) of the chondrocytes, leaving behind empty lacunae that are eventually invaded by osteogenic cells.
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More Bone Growth questions
- In the process of bone remodeling during growth, why must bone resorption occur on the internal surface of the diaphysis?
- What remains of the epiphyseal plate once an individual reaches skeletal maturity?
- Which signaling molecule is essential for the transition from mesenchymal cells to osteoblasts during intramembranous ossification?
- What is the function of the 'Periosteal Bud' during endochondral ossification?
- Which nutritional factor is specifically required for the hydroxylation of proline in the collagen matrix during bone growth?
- How does the 'Zone of Ossification' (or Resorption) differ from the 'Zone of Calcification'?