Bone Growth · Histology

How does the 'Zone of Ossification' (or Resorption) differ from the 'Zone of Calcification'?

  1. It contains proliferating chondrocytes secreting new cartilage matrix.
  2. It features osteoblasts depositing bone on calcified cartilage remnants.
  3. It is the region where the periosteal bony collar forms around the diaphysis.
  4. It is composed of fibrocartilage that cushions against compressive loading.
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Correct answer: It features osteoblasts depositing bone on calcified cartilage remnants.

The zone of ossification is the final stage at the epiphyseal plate. Here, blood vessels and osteoblasts invade the spaces left by dead chondrocytes, and osteoblasts lay down a 'mixed spicule' of bone on top of the calcified cartilage remnants.

Difficulty: Medium Question 15 of 20

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